Mapping quiescence of hematopoietic stem cells
There is a common assumption that adult stem cells in our body actively divide only in case of regeneration of damaged tissues, at least in the hematopoietic system. In steady-state conditions...
View ArticleRegulation of leukemic stem cells self-renewal and quiescence – the role of p21
A new study published in Nature indicated that a well-known cyclin-dependent inhibitor (CDI), p21 can actually protect the leukemic stem cell pool through limiting DNA damage, keeping them in a...
View ArticleRevised: Cell cycle kinetics of hematopoietic stem cells
Note: There is a print link embedded within this post, please visit this post to print it. Intro: Cell cycle kinetics of the hematopoitic stem cell (HSC) population is very important in normal...
View Article